Some schizophrenia patients become less prone to violence when taking medication, but those with a history of childhood conduct problems continue to pose a higher risk even with treatment, according to a new study by researchers at Duke University Medical Center. “This is the first large randomized controlled study to compare the effectiveness of several [...]
People with schizophrenia bear an “increased burden” of rare deletions and duplications of genetic material, genome-wide, say researchers supported in part by the National Institute of Mental Health (NIMH), a component of the National Institutes of Health (NIH). “Although many of us have these changes in our genetic material, they are about 15 percent more [...]
People with schizophrenia have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes. These results were published today in the scientific journal Nature. Research scientists found changes in the structure of the genes in patients with schizophrenia when they studied what are known [...]
Scientists from the University have identified a risk gene associated with the mental health disorder schizophrenia. An international group of researchers, led by Professors Michael O’Donovan, Nick Craddock, and Michael Owen from the School of Medicine examined DNA samples from over 7,000 individuals with schizophrenia, and almost 13,000 people without the disorder. Their findings, which [...]
Large multinational study reveals rare structural DNA changes play role in schizophrenia. The delusions and hallucinations of schizophrenia can be devastating for the 1% of the population struck by the disease. The condition clearly has a genetic component, evidenced by its tendency to run in families. However, the search for specific genes or chromosomal regions [...]
University of Iowa researchers contributed to a study that found a particular genetic variation is associated with schizophrenia. The severe mental health disorder affects nearly 1 percent of people in the United States and can include delusions, hallucinations and confused thinking. The study, which was published online July 30 in the journal Nature Genetics, was [...]
People with schizophrenia have an alteration in a pattern of brain electrical activity associated with learning and memory. Now, researchers from the National Institutes of Health and Sweden’s Karolinska Institute have identified in mouse brain tissue a molecular switch that, when thrown, increases the strength of this electrical pattern. The researchers found that adding the [...]
Childhood bedwetting occurred twice as often in adults with schizophrenia than in their unaffected brothers and sisters, according to a new study from researchers at NIMH. Their report appears in the September 2008 issue of the journal Brain. In the study led by NIMH’s Thomas M, Hyde, M.D., Ph.D., the mothers of 211 adult schizophrenia [...]
Two newer atypical antipsychotic medications were no more effective than an older conventional antipsychotic in treating child and adolescent schizophrenia and may lead to more metabolic side effects, according to a new study funded by the National Institutes of Health’s National Institute of Mental Health (NIMH). “Schizophrenia and schizophrenia-related disorders are rare in childhood. But [...]
Schizophrenia is a severe psychiatric disease characterized by disorganized behavior, delusions and hallucinations. Sadly, there is no clear understanding of its cause. Now, in a collaborative study, UCLA and Dutch researchers have identified three new candidate genes for schizophrenia that may contribute to a better understanding of how the disease evolves. Reporting in the October [...]
